Debra N Brunson

Debra N Brunson,

Postdoc

Department: DN-ORAL BIOLOGY
Business Phone: (352) 392-2310
Business Email: d.brunson@ufl.edu

About Debra N Brunson

Debra received her bachelor’s degree in Microbiology from Idaho State University where she developed her interest in host pathogen interactions. She also received an master’s in biology from the University of North Florida, where she studied the impacts of outer membrane porin loss on the physiology of Klebsiella pneumoniae. In 2023, Debra graduated from the Biomedical Sciences Ph.D. program at UF. Her project focused on the characterization of iron transporters and interpreting the importance of iron homeostasis to virulence of Enterococcus faecalis. After graduation, Debra chose to remain in the Lemos-Abranches lab to further her research into mechanisms of heme utilization by E. faecalis as a postdoctoral associate.

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-2346-4652

Publications

2024
Heme utilization by the enterococci
FEMS Microbes. [DOI] 10.1093/femsmc/xtae019.
2023
Identification of Multiple Iron Uptake Mechanisms in Enterococcus faecalis and Their Relationship to Virulence
Infection and Immunity. 91(4) [DOI] 10.1128/iai.00496-22. [PMID] 36912636.
2023
Optimized replication of arrayed bacterial mutant libraries increase access to biological resources.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.04.25.537918. [PMID] 37162974.
2023
Optimized Replication of Arrayed Bacterial Mutant Libraries Increases Access to Biological Resources.
Microbiology spectrum. 11(4) [DOI] 10.1128/spectrum.01693-23. [PMID] 37432110.
2022
Dual species biofilms are enhanced by metabolite cross-feeding.
Trends in microbiology. 30(9):809-811 [DOI] 10.1016/j.tim.2022.07.003. [PMID] 35871025.
2022
Methods for Using the Galleria mellonella Invertebrate Model to Probe Enterococcus faecalis Pathogenicity.
Methods in molecular biology (Clifton, N.J.). 2427:177-183 [DOI] 10.1007/978-1-0716-1971-1_15. [PMID] 35619034.
2022
The AdcACB/AdcAII system is essential for zinc homeostasis and an important contributor of Enterococcus faecalis virulence.
Virulence. 13(1):592-608 [DOI] 10.1080/21505594.2022.2056965. [PMID] 35341449.
2019
Porin loss in Klebsiella pneumoniae clinical isolates impacts production of virulence factors and survival within macrophages
International Journal of Medical Microbiology. 309(3-4):213-224 [DOI] 10.1016/j.ijmm.2019.04.001.
2015
Porin Loss Impacts the Host Inflammatory Response to Outer Membrane Vesicles of Klebsiella pneumoniae.
Antimicrobial agents and chemotherapy. 60(3):1360-9 [DOI] 10.1128/AAC.01627-15. [PMID] 26666932.

Grants

Jan 2022 – Dec 2023
Significance of iron homeostasis to the pathophysiology of Enterococcus faecalis during infective endocarditis
Role: Principal Investigator
Funding: AMER HEART ASSOCIATION

Contact Details

Phones:
Business:
(352) 392-2310
Emails:
Business:
d.brunson@ufl.edu
Addresses:
Business Mailing:
PO Box 112010
GAINESVILLE FL 32611
Business Street:
PO Box 112010
GAINESVILLE FL 32611